Proteome Data Integration: Characteristics and Challenges

نویسندگان

  • K. Belhajjame
  • S. M. Embury
  • H. Fan
  • C. Goble
  • H. Hermjakob
  • S. J. Hubbard
  • D. Jones
  • P. Jones
  • N. Martin
  • S. Oliver
  • C. Orengo
  • N. W. Paton
  • A. Poulovassilis
  • J. Siepen
  • R. D. Stevens
  • C. Taylor
  • N. Vinod
  • L. Zamboulis
  • W. Zhu
چکیده

The aim of the ISPIDER project is to create a proteomics grid; that is, a technical platform that supports bioinformaticians in constructing, executing and evaluating in silico analyses of proteomics data. It will be constructed using a combination of generic e-science and Grid technologies, plus proteomics specific components and clients that embody knowledge of the proteomics domain and the available resources. In this paper, we describe some of our earlier results in prototyping specific examples of proteomics data integration, and draw from it lessons about the kinds of domain-specific components that will be required.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

I-3: Human Y Chromosome Proteome Project 2012 Update

The Human Genome Project has generated a blueprint for the approximately 20,300 gene-encoded proteins potentially active in any of 230 cell types that make up the human body (human proteome). However, based on the UniProtKB/Swiss-Prot database content, about 6000 of at the protein level; for many others, there is very little information related to protein function, abundance, subcellular locali...

متن کامل

Significant Characteristics of Multi Carrier Energy Networks for Integration of Plug-In Electric Vehicles to Electric Distribution Network

One of the big concerns of big cities is facing with the increase of fossil fuel vehicles in the roads. The cars intensify greenhouse gas emission in civic centers. One approach to reduce the emission is replacing the cars by Plug-In Electric Vehicles (PEVs). In spite of reducing the emission, PEVs have some adverse effect on electric distribution networks. Technical challenges such as load and...

متن کامل

Data management and preliminary data analysis in the pilot phase of the HUPO Plasma Proteome Project.

The pilot phase of the HUPO Plasma Proteome Project (PPP) is an international collaboration to catalog the protein composition of human blood plasma and serum by analyzing standardized aliquots of reference serum and plasma specimens using a variety of experimental techniques. Data management for this project included collection, integration, analysis, and dissemination of findings from partici...

متن کامل

3D and 4D Seismic Data Integration in Static and Dynamic Reservoir Modeling: A Review

Reservoir modeling is the process of generating numerical representations of reservoir conditions and properties on the basis of geological, geophysical, and engineering data measured on the Earth’s surface or in depth at a limited number of borehole locations. Therefore, reservoir modeling requires an incorporation of the data from a variety of sources, along with an integration of knowledge a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005